Abstract The cell/microenvironment interface is the starting point of integrin-mediated mechanotransduction, but many details of mechanotransductive Cat toys signal integration remain elusive due to the complexity of the involved (extra)cellular structures, such as the glycocalyx.We used nano-bio-interfaces reproducing the complex nanotopographical

Primary microcephaly (MCPH), is a neurological disorder characterized by small brain size that results in numerous developmental problems, including intellectual disability, motor and speech delays, and seizures.Hitherto, over 30 MCPH causing genes (MCPHs) have been identified.Among these MCPHs, MCPH5, which encodes abnormal spindle-like Solid Hotp

After failure of a column in structure by an abnormal loading, undesirable performance KNIFE PARTS and damage of connections of the beams connected to the top of this column, can lead to the local failure of floor and in turn result in progressive collapse in the structure.Accordingly, the best method for rehabilitation of the structure against thi

There are two critical parameters for microbolometers: the temperature coefficient of resistance (TCR) of the sensing material, and the thermal conductance of the insulation structure.Cytochrome c protein, having a high TCR, is a good candidate for infrared detection.We can use SU-8 photoresist for the thermal insulation structure, given its low th

Real-time surveillance is a crucial element in the response to infectious disease outbreaks.However, the interpretation of incidence data is often hampered by delays occurring at various stages of data gathering and reporting.As a result, recent values are biased downward, which obscures current trends.Statistical nowcasting techniques can be emplo